Semaglutide 2.5mg – Paradigm Peptides

Semaglutide 2.5mg

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Semaglutide

Paradigm Peptides manufactures semaglutide for sale at the highest quality and potency available. Semaglutide is a medication commonly used for treatment in diabetes, weight loss, and weight management.

 

All products currently listed on this site are for research purposes only and not for human consumption.

Application: Used to treat type 2 diabetes, obesity, and weight loss management
CAS: 910463-68-2
Molecular Weight: 4113.641 g·mol−1
Chemical Formula: C187H291N45O59
Chemical Name: Pyroglutamyl-histidyl-tryptophyl-seryl-tyrosyl methyl ester
Synonyms: Ozempic, Rybelsus, Wegovy
Storage: Minimize open air exposure, store in a cool dry place.
Stability: 2 Years
Purity: 99%
Solubility: Soluble in water at a rate of 4mg/mL
Organoleptic Profile: Powder
Physical Form: Crystalline powder
Specifications: 2.5mg
Container: 2.5mg vial
Terms: The products we offer are intended for laboratory research use only. You will need to purchase Bacteriostatic water separately.

 

What is Semaglutide?

Semaglutide, or Ozempic when sold under its brand name, is an anti-diabetic medication. It is most commonly used as a treatment for type 2 diabetes as well as a treatment for obesity and weight management. It is a GLP-1 receptor agonist which means that it can mimic the action of incretin glucagon like peptide 1. The results include increased insulin secretions coupled with an increase in blood sugar disposal. Meaning that overall glycemic control is improved.

 

Researchers at Novo Nordisk developed semaglutide as an alternative to liraglutide. Their aim was to replace liraglutide with a once a week diabetes medication.

 

Upon further research in 2017, semaglutide was also reported by both the University of Leeds and Novo Nordisk to aid as a treatment for obesity as well as a treatment for type 2 diabetes. A randomized controlled trial of semaglutide found that a singular dose a week resulted in a loss of 15% body weight over a 68 week span.

 

Semaglutide: A Study on Obesity

Obesity is a global health problem; however, with the help of peptides such as semaglutide, adults with obesity can achieve weight loss more effectively. And maintain said weight loss over time. In a double blind trial, adults with a higher body mass index of greater than 30 who did not have diabetes were randomly assigned to either placebo or semaglutide dosing once a week. This study spanned 68 weeks of treatment. In the group treated with semaglutide, the participants saw a 14.9% decrease in weight over the time frame as compared to the placebo group which only lost 2.4% of their body weight. Of the 1,961 participants, 1047 achieved 5% or more weight loss. The dosage given to participants in the semaglutide group was 2.4mg once weekly.

 

Keep in mind that the semaglutide on its own was not the only factor in this study. As it was coupled with lifestyle changes in the participants that included diet and exercise related changes.

 

Benefits & Side Effects

By mimicking the action of incretin GLP-1 in the body, semaglutide achieves several benefits for its users. The most common benefits being the lowering of blood sugar levels and the reduction in weight. When using semaglutide, it reduces the need for food intake in two ways. The first is a lowering of appetite and the second is slowing down digestion in the stomach. In doing these two things, semaglutide reduces food craving and hunger which then reduces body weight over time.

 

  • Weight reduction
  • Lessened appetite
  • Slower digestion
  • Type 2 diabetes management

 

As for adverse side effects, several do exist which include nausea or vomiting, abdominal pain, and constipation. Something important to note is that in patients experiencing heart problems, semaglutide does have the possibility to cause damage to the retina of the eye.

 

  • Nausea or vomiting
  • Abdominal pain
  • Constipation

 

At higher doses that exceed recommendations, semaglutide has the potential to cause kidney damage, pancreatitis, and low blood sugar.

 

  • Low blood sugar
  • Pancreatitis
  • Kidney Damage

 

Semaglutide: Dosing Protocol

Unlike many other treatment options, semaglutide does not require daily dosing in order to achieve the outcome sought after. That being said, dosages do range from 0.25mg per week to 2mg per week. It is highly recommended to start at the lower dose of 0.25mg for the first four weeks of use and then for the proceeding four weeks you can up that dose to the 0.5mg dosage. If additional dosing is needed that is when you can up the dose to 1mg or 2mg per week. However, it is not recommended to exceed the 2mg dose per week.

 

Weeks 1-4: 0.25mg per week

Weeks 5-8: 0.5mg per week

Any preceding weeks, only increase up to 2mg per week if needed.

 

Something to note if taking semaglutide as a weight loss element. It primarily works when coupled with lifestyle changes that include both changes in diet as well as exercise. Those seeking to use semaglutide as a dietary aid will want to take 2.4mg once a week over the course of a year or more. Immediate changes may not be notable as it does take time for the weight loss to occur with the use of semaglutide.

 

Peptides from Paradigm Peptides

At Paradigm Peptides, we’re a premium manufacturer of high-quality research products. We are dedicated to ensuring every one of our customers finds exactly what they’re looking for. All of our products undergo stringent testing for efficacy and potency prior to becoming available on our site. If you’re looking for peptides, SARMs, or nootropic supplements, contact us today for more information about our selection.

 

*Disclaimer: Semaglutide for sale on this site is sold for research use only. Not for human consumption. This product is not a drug, supplement, food or cosmetic, and it may not be misused, sold, labeled or branded as such. These products are not intended to diagnose, treat, or cure any condition or disease.

 

Research:

https://onlinelibrary.wiley.com/doi/abs/10.1111/obr.12839

https://www.tandfonline.com/doi/full/10.1080/17425255.2018.1488965

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750268/

https://www.sciencedirect.com/science/article/abs/pii/S221385871730013X

https://jamanetwork.com/journals/jama/article-abstract/2657376

https://www.sciencedirect.com/science/article/abs/pii/S0140673621002130

https://insight.jci.org/articles/view/133429?utm_source=notices&utm_medium=email&utm_content=link&utm_campaign=JCI+Insight+-+March+26%2C+2020%2C+issue+published

https://www.nejm.org/doi/full/10.1056/NEJMoa1607141

https://onlinelibrary.wiley.com/doi/full/10.1002/oby.22794

Weight .25 oz

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