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Effects of Phenibut Nootropic

Phenibut is increasingly becoming one of the world’s most popular and versatile smart drugs. While the Phenibut nootropic was first developed as a treatment for anxiety, researchers soon recognized its effects as having characteristics that extend far beyond improving stress. Today, students and CEOs alike use Phenibut to help strengthen their cognitive functions, improve mood and enhance memory.

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Paradigm Peptides manufactures Phenibut for sale at the highest quality and potency available. Phenibut comes from Gamma-Aminobutyric Acid, or GABA for short. This is a neurotransmitter that is tasked with lowering stress and improving your moods. 

All products currently listed on this site are for research purposes only and not for human consumption.

Application: neurotransmitter that improves mood and lowers stress levels
CAS: 3060-41-1
Molecular Weight: 179.219 g/mol
Chemical Formula: C10H13NO2
Chemical Name: β-Phenyl-γ-aminobutyric acid
Synonyms: fenibut, phenybut, and Citrocard
Storage: Should be stored in a cool, dark and dry space
Stability: 2 Years
Purity: 99%
Solubility: 35 mg/mL in water
Organoleptic Profile: Bitter taste, crystalline powder
Physical Form: Solid, powder form
Specifications: 250mg per Capsule
Container: 90 Capsules per Bottle
Terms: The products we offer are intended for laboratory research use only.

The Importance of GABA and GABA Receptors

GABA, or γ-Aminobutyric acid is a chief inhibitory neurotransmitter in our central nervous systems. GABAs primary role is to reduce the excitability of our neurons in our nervous system. But all GABA are not the same. In fact, their are two types. The first is GABAa, the second GABAb. 

GABAa have receptors that are part of the ligand-gated ion channel complex, or ionotropic receptors. These are a grouping of transmembrane ion channel proteins. They allow for the opening of channels so that ions can pass through membranes as a response to binding of a chemical messenger. 

GABAb are metabotropic receptors. These receptors are G protein-coupled receptors and open or close ion channels through intermediaries. 

What is Phenibut?

The nootropic phenibut first made its appearance in the Soviet Union back in the 1960s. At the time it was being researched as an anti-anxiety and insomnia medication for patients. Because of how it works, it is able to work as a depressant in addition to having anxiolytic effects. 

Phenibut is a derivative of the inhibitory transmitters known as GABA. It is therefore a GABA analogue. Since GABA is the primary inhibitory transmitter in our nervous system, it is important to know how phenibut will affect it and what GABA does. GABA has a primary role in reducing excitability of neurons in our nervous systems. The biggest difference between GABA and phenibut is that phenibut has the ability to pass through our blood-brain barriers. How is it possible? The nootropic has a ring of phenyl attached to it which allows for it. 

While its primary use is for depression and asthenia, researchers have also used it as a possible treatment for those who suffer from alcoholism.

Sensory & Tactile Function

Rats given a middle cerebral artery occlusion, or MCAO, were monitored for  sensory and tactile functions as well as histological outcomes. Researchers induced MCAO by filament insertion or ET1 microinjection. Phenibut was then administered by researchers at 10mg and 50mg per kilogram of weight. This was done over the course of two weeks. 

By the conclusion of the experiment, researchers were able to surmise that doses of phenibut had the ability to provide neuroprotective measures.

Benefits & Side Effects of Phenibut

When looking into the different benefits of phenibut, the list is fairly extensive. It has been noted to assist with stress, depression and anxiety. And has also made a significance in the ability to get more restful sleep. 

Another common but not well known benefit of phenibut is increase to cognitive function as well as your sex drive.

Benefits of Phenibut Use:

  • Improved memory
  • Lower Levels of Stress, Depression & Anxiety
  • Better Sleep – Especially Amongst Those With Insomnia
  • Enhanced Cognitive Function
  • Stronger Critical Thinking Skills
  • Increased Sexual Drive
  • Neuroprotection
  • Cardioprotection

But of course, as with most compounds, there is a possibility for side effects. In most case studies, phenibut was well tolerated. However, some individuals did experience side effects including dizziness, nausea, headaches, and sleepiness. 

Something to make note of is that over time your body may build up a tolerance to the nootropic. When a tolerance is built up over time with the dosage being consistently increased, there have been notations of rebounding with both anxiety and insomnia in some patients. 

Dosing with Phenibut

When it comes to Phenibut there is not a specific dose for everyone. It depends on several factors such as the person’s age and overall health. Of course, while their is not a specific dose, there are some guidelines. 

For example, it is recommended that you start with a 250mg/day dosage when first beginning to take phenibut and gradually build up to 1-2 grams per day. Phenibut can be habit-forming if taken in excess. With that in mind, correct usage and proper dosages are strongly advised.

Buying Nootropics from Paradigm Peptides

Paradigm Peptides is a trusted source of the world’s best nootropics, peptides and SARMs. If you’re ready to kick anxiety to the curb and boost your overall mental health, you can buy phenibut online from our store today. 

If you’re not sure that it is the right nootropic for you, then feel free to reach out to our friendly and knowledgeable customer service team via email at [email protected] They are more than happy to educate you on our various products so that you can make the best choice for you.

*Disclaimer: The phenibut currently listed on this site is sold for research use only. Not for human consumption. This product is not a drug, supplement, food or cosmetic and it may not be misused, sold, labeled or branded as such.These products are not intended to diagnose, treat, or cure any condition or disease.


Weight 2 oz
Dimensions 2 × 2 × 3 in