MOTS-c (10mg)

MOTS-c

Paradigm Peptides manufactures MOTS-c for sale at the highest quality and potency available. The MOTS c peptide is a shortened variation of a mitochondrial-derived peptide. It plays important roles in several areas of your body including both metabolism and the regulation of weight.

 

All products currently listed on this site are for research purposes only and not for human consumption.

Application:	Aids in energy regulation of several attributes
CAS:	1627580-64-6
Molecular Weight:	2174.6 g/mol
Chemical Formula:	C101H152N28O22S2
Chemical Name:	H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH
Synonyms:	UNII-A5CV6JFB78; A5CV6JFB78; Mitochondria-derived peptide mots-c; EX-A6267
Storage:	Minimize open air exposure, store in a cool dry place.
Stability:	2 Years
Purity:	99%
Solubility:	Soluble in water
Organoleptic Profile:	Powder
Physical Form:	Crystalline powder
Specifications:	10mg
Container:	10mg vial
Terms:	The products we offer are intended for laboratory research use only. You will need to purchase Bacteriostatic water separately.

 

What is MOTS-c?

MOTS-c, or mitochondrial-derived peptide MOTS-c, is the SSU rRNA of the mitochondrial ribosome. This is just a fancy way of saying it is a protein complex that’s typically active in mitochondria. It functions as a riboproteins which helps in the translation of mitochondrial mRNA ensconced in mtDNA.

 

Humans tend to have a progressive loss of metabolic homeostasis when aging. This impedes various functions which lead to diminished physical abilities. As a way to determine if MOTS-c responds to physical activity, one study collected skeletal muscle and plasma from sedentary young male participants. These were collected before, during, and after physical activity. It was found in this study that MOTS-c did increase significantly during and after the exercise. These findings suggest that exercise may have an effect on MOTS-c in the body.

 

For those looking to use synthetic MOTS-c, it has shown an affinity to aid in mitochondrial communication as well as energy regulation in its users. While it was originally believed to be only related to mitochondrial tasks, new research has shown that it can also make its way to the bloodstream for a more holistic effect on the body. It has the ability to aid in several areas including the metabolism, the regulation of weight, and exercise longevity.

 

Not only that, MOTS-c may also show an affinity to aid in the treatment of conditions such as osteoporosis as well.

 

Research on MOTS-c

In one clinical study on mice, the MOTS-c peptide showed an affinity to reverse age-dependent insulin resistance in various muscles. Insulin is a peptide hormone produced in the pancreas and helps blood sugar enter blood cells. This is so that it can be used as energy. Therefore, MOTS-c reversing age-dependent insulin resistance has the potential to lead to the improvement of our body’s muscle uptake of glucose.

 

Now, since it is able to assist in the reversal of insulin resistance, it also by default has the ability to aid in the metabolism in fat mass. This is possible because when MOTS-c was introduced to mice it helped in the increase of brown fat function and the reduction of what is known as adipose tissue. Other things to note about the peptide MOTS-c is that it also showed an ability to prevent adipose dysfunction and inflammation in its subjects as well.

 

MOTS-c Benefits & Side Effects

MOTS-c peptide does several things for the body when taken. Primarily it aids with the metabolism and mitochondrial energy. However, it has also shown an affinity as a protection against age and diet dependent insulin resistance and subsequent obesity.

 

• Promotes fatty acid metabolism (primarily in the liver)
• Promotes metabolic homeostasis & flexibility
• Regulates mitochondrial energy
• Aids weight loss
• Improves exercise capacity
• Muscle Gain
• Prevention of osteoporosis

 

As of now, there are minimally known side effects for those that take MOTS-c peptide. While it has excellent bioavailability subcutaneously it should be noted that it is not as effective when taken orally.

 

Proper MOTS-c Dosing Protocol

After reconstitution with either bacteriostatic water or sterile water, which usually consists of 1mL to 2mL of solution, you’ll want to ensure that your product has dissolved. It is important to note that you never want to violently shake the bottle or spray your peptide directly with solution. This will render it completely useless. Instead, drizzle the solution down the side of the vial and let the peptide mix on its own.

 

Based on animal studies, researchers believe that it is best to administer MOTS-c peptide in the morning as it has the possibility to interfere with your sleep schedule otherwise. It is recommended that those that take MOTS-c dose every 5 days and administer a dose of 5mg per day. The dose may need to be adjusted as needed depending upon the person and their specific medical background.

 

Based on the dosing protocol above, an individual using MOTS-c for weight loss would need two of our 10mg vials to complete their one month study.

 

Paradigm Peptides: A Trusted Source for Peptides

At Paradigm Peptides, we’re a premium manufacturer of high-quality research products. As a company, we are dedicated to ensuring every one of our customers finds exactly what they’re looking for. If you’re looking for peptides, SARMs, or nootropic supplements, contact us today for more information about our selection.

 

*Disclaimer: MOTS-c for sale on this site is sold for research use only. Not for human consumption. This product is not a drug, supplement, food or cosmetic, and it may not be misused, sold, labeled or branded as such. These products are not intended to diagnose, treat, or cure any condition or disease.

 

Research:

https://pubchem.ncbi.nlm.nih.gov/compound/146675088#section=Structures

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350682/

https://journals.physiology.org/doi/full/10.1152/ajpendo.00275.2020

https://www.mdpi.com/1422-0067/23/19/11991

https://www.sciencedirect.com/science/article/pii/S2211124721008640

https://www.nature.com/articles/s41598-021-93735-2

https://www.nature.com/articles/s41598-021-99568-3

https://www.mdpi.com/1422-0067/22/16/8770

https://dm5migu4zj3pb.cloudfront.net/manuscripts/158000/158449/JCI158449.v1.pdf

https://link.springer.com/article/10.1007/s11325-020-02273-0

https://link.springer.com/article/10.1007/s13239-021-00589-w

https://www.nature.com/articles/s41467-020-20790-0

https://link.springer.com/article/10.1007/s00109-018-01738-w