Cardarine GW-501516 SARM

Paradigm Peptides manufactures cardarine for sale at the highest quality and potency available. Cardarine, which researchers also refer to Cardarine GW 501516 or endurobol, is a PPARδ receptor agonist. These receptors rule over various biological processes. In the case of most available GW-501516 for sale, research shows that it binds to these receptors and thus activates AMP-activated protein kinase. According to research findings, these proteins are in charge of energy production and promote and secure the ability to survive during metabolic stress. By activating the AMP-activated protein kinase, GW-501516 potentially can initiate a rapid increase in fat lipolysis and overall energy output.

All products currently listed on this site are for research purposes only and not for human consumption.

SARMs are not evaluated by the FDA, nor are they allowed by WADA.

Name:	GW-501516 (Cardarine)
CAS:	317318-70-0
Molecular Formula:	C21H18F3NO3S2
Molecular Weight:	453.498 g/mol
Specification:	10mg / Tablet
Container:	60 Cardarine capsules

Trust Paradigm Peptides as your number one source to buy selective androgen receptor modulators (SARMs) online. The SARM cardarine is touted as a highly effective endurance SARM.

Because of it’s popularity, athletes often consider cardarine for its purported benefits, which include improved overall athletic performance. Also known as GW-501516, cardarine can help lower LDL cholesterol and increase muscle mass and regeneration — notes Johannah Gregg, Certified Family Nurse Practitioner and Peptide Therapy Specialist — to help you look and feel your best. Our GW-501516 Cardarine capsules are 10 mg each and come in a bottle of 60! Order your Cardarine SARMs for sale today from Paradigm Peptides.

About Cardarine SARM

Cardarine is a synthetic compound that is sometimes used by athletes as an additional method to support the metabolism. While cardarine is often referred to as a SARM, it is actually a peroxisome proliferator-activated receptor delta (PPAR delta) receptor agonist.

SARMs function similarly to steroids in that they bind to androgen receptors in the body. However, they have lower androgenic properties compared to anabolic steroidsand are specially formulated to target certain parts of the body. This primarily includes muscle and bone. Because of the mechanism in which they work they’re known for having fewer side effects than anabolic steroids.

By comparison, PPARs like cardarine do not bind to androgen receptors or contribute to anabolic activity, nor do they affect the production of testosterone. PPARs like cardarine can help support endurance but do not act as stimulants, which means your sleep and cortisol should not be affected.

Cardarine is one of three members of the PPAR group and is a ligand-activated transcription factor. A ligand-activated transcription factor is a DNA-binding transcription factor activity that is regulated by binding to a ligand. Generally speaking, it modulates the transcription of a specific gene set.

Like most compounds, Cardarine also has many other names, such as GW-501516, GW1516, GSK-516, and Endurobol, depending on the manufacturer. Cardarine showspotential in the aiding of fat burning as well as assisting in the prevention of obesity in its users.

As previously mentioned, cardarine is popular among athletes because of its effects on energy metabolism within the cells of the muscles and its potential to encourage energy expenditure. By supporting energy metabolism, researchers have discovered that cardarine may help to synthesize fat-burning, promote a leaner body composition, and support athletic performance.

Cardarine works by influencing genes that are responsible for fatty acid oxidation, which can encourage energy production and support your body’s endurance levels while you’re working out.

Studies on Cardarine

Cardarine was developed in the 1990s as part of a research collaboration by pharmaceutical companies GSK and Ligand Pharmaceuticals. Over the last 30 years it has undergone numerous studies. The studies have primarily been conducted in animals; however, many of these studies have indicators for the use of cardarine in human subjects.

Some of these research trials have tested cardarine for its effects on obesity, the brain, muscle gain, and diabetes as well as many other possible applications. Results from a selection of these studies are summarized below.

The Brain

When it comes to the brain, a study was done not with living, breathing rats but instead with a cluster of brain cell cultures that had been prepared using embryonal rat brain. The study examined the effects of cardarine on inflammatory responses that were triggered by the interferon gamma (IFN-gamma) and lipopolysaccharide (LPS).

IFN-gamma is a dimerized soluble cytokine and is the only member of the type II class of interferons. Basically, what this means is that it combines with similar molecules to form what is called a dimer. This molecule is made of two identical molecules that are linked together.

Lipopolysaccharides are large molecules that consist of a lipid and polysaccharide and are found in the outer membrane of gram-negative bacteria. The basis of the study was to see what would happen to these two substances when cardarine is introduced. The results of the study concluded that cardarine reduced IFN-gamma-induced up-regulation on TNF-alpha and iNOS as well as had anti-inflammatory effects.

Blood Sugar

One study conducted on rats examined the effects of cardarine on animals with high blood sugar during pregnancy.

When administered to these rats, cardarine was shown to support healthy blood glucose insulin levels. [1] This means it may help support proper insulin sensitivity.

Another study found that cardarine may have benefits for people dealing with diabetic wounds. These types of injuriesare common in people with uncontrolled blood sugar as a result of reduced blood flow to the extremities, particularly the feet. The study found that cardarine may help by contributing to the healing process of the wounds. [2]

Maintaining Heart Health With Cardarine

In a 12-week study, human patients were given cardarine (GW-501516) at varying dosages; these dosages included 2.5mg, 5.0mg, and 10mg. Participants in the study were relatively healthy individuals with a high-density lipoprotein (HDL) level of < 1.16mmol/L.

Commonly known as “bad cholesterol,” HDL is an important factor in the development of cardiovascular disease in humans. Higher levels of HDLs are correlated to higher incidences of cardiovascular disease.

When the study was at the beginning stages, a number of tests were conducted in order to create a baseline for the participants involved, including fasting insulin, glucose, lipids, and free fatty acid levels.

By the end of this 12-week study, participants had experienced a significant change in both cholesterol levels, meaning HDL and low-density lipoprotein (LDL). It was therefore concluded that cardarine has potential as a cardiovascular protection compound.

Obesity and Weight Loss With Cardarine SARMs

Two notable studies existthat examine the effects of cardarine usage on both obesity and fat loss.

On a smaller scale study, six rhesus monkeys at the University of Maryland were subjected to a specific diet consisting of 13% fat, 18% protein, and 69% carbohydrates, which was anticipated to result in increased weight gain in the subjects. During the study of cardarine and its effects on these monkeys, each monkey was given initial doses of 0.1mg/kg daily.

By the end of the study, these same monkeys were administered 3.0mg/kg each day. The study found that, by giving the monkeys a “treat” twice a day, in which cardarine was its main ingredient, these monkeys consumed less food overall. Therefore, researchers concluded that cardarine could be helpful in addressing obesity and minimizing the risk of overeating.

Another study in animals seemingly confirms the potential effects of cardarine on obesity. A study conducted on wild-type mice placed the animals on a high-fat diet with a significant increase in fats from their overall diet; compared to a diet with 4% fat content, these mice were placed on a diet that consisted of 35% fat content.

Over the course of a 2-month span, these mice saw a 30% increase in body weight but also showed an improvement in their glucose tolerance as well as a reduction in fat mass. The implications for humans are that cardarine may help us burn body fat while encouraging lean muscle growth. This can easily translate to benefits for athletes trying to build muscle tissue while reducing total body fat.

Dosage Protocol for Cardarine Capsules

Cardarine dosage is easy to understand. For starters, a typical dosage cycle of GW 501516 lasts about eight weeks. You will change the dosage once during the cycle, after which point the dosage will remain the same for the remainder of the cycle.

For the first week, it is recommended that you start out at 10mg. This dose will allow your body to get used to the cardarine. After that initial first week, you can then bump your dose up to 20mg per day for the remainder of the cycle.

Human studies conducted in the early 2000s studied cardarine doses of up to 10 mg per day for the treatment of high density lipoprotein (HDL) cholesterol and triglycerides in the blood. [5] These studies found that no adverse effects occurred at this level of usage.

Unlike other products, such as testolone or ostarine, you do not necessarily need to complete a PCT. However, it is still important that you give your body time off after the cycle to let it recuperate.

Pros & Cons: Cardarine SARMs

In most cases, there are some mild side effects to keep in mind when using any new substances. However, these side effects are often insignificant when considering the benefits. Side effects are often most prominent when first starting use of a new substance, but they may subside over time as the body becomes accustomed to the substance.

Cardarine may offers a number of different benefits, particularly for athletes and those looking to take their workouts to the next level.

Being able to do longer and tougher workouts can help build strength and endurance, encouraging overall performance. On top of this, you’ll be able to increase muscle mass as well as maintain it without the accompanying increase in body fat that sometimes results from eating more.

While cardarine works well to help you accomplish your athletic goals, it cannot replace a healthy diet. Therefore, you will want to ensure that you monitor your diet and exercise while using cardarine to ensure maximum results are achieved.

In addition to a healthy diet and exercise, remember todrink plenty of water while taking cardarine so that you stay properly hydrated for your longer, tougher workouts.

There are a few things to keep in mind if you are considering taking cardarine. Cardarine should not be used by people who are pregnant or are planning to become pregnant due to potential health risks.

Cardarine also should not be purchased by individuals in Australia, as the country has banned the use of the substance within its borders.

Paradigm Peptides

Ready to start your journey with cardarine today? Paradigm Peptides provides top quality authentic peptides, SARMs, and research chemicals. Many companies online offer cardarine for sale; however, not many are reputable like Paradigm Peptides. As a company we work hard to ensure efficacy, potency, and purity as a way to stand out from the competition.

As mentioned previously,when you buy cardarine online through us, you will receive your high-quality SARMs in a container containing 60, 10mg tablets. Purchase your high-quality SARMs for sale online at Paradigm Peptides today.

Disclaimer: The Cardarine GW 501516 currently listed on this site is sold for research use only. Not for human consumption. This product is not a drug, supplement, food, or cosmetic, and it may not be misused, sold, labeled, or branded as such.These products are not intended to diagnose, treat, or cure any condition or disease.

Medically Reviewed By: Johannah Gregg, DNP FNP-C

Research:

• https://www.ajconline.org/article/S0002-9149(07)01592-5/fulltext
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5492977/
• https://web.archive.org/web/20150504013406/
• http://www.toxicology.org/AI/PUB/Tox/2009Tox.pdf
• https://academic.oup.com/mend/article/17/12/2477/2747399
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386117/
• https://pubmed.ncbi.nlm.nih.gov/17110604/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335770/
• https://pubmed.ncbi.nlm.nih.gov/25449811/