Have you ever wondered why other bodybuilders or fitness enthusiasts rave about taking things like Sildenafil or Tadalafil? It’s not just to do with their erections. In fact, these compounds can do some much more. Whether that means treating medical conditions or helping you get shredded fast. Ready to learn just how this compound can help? Then let’s get started with a simple break down of what it really is and how It works.

What is Tadalafil?

Tadalafil, better known under its brand name as Cialis, is a medication for treating erectile dysfunction, pulmonary arterial hypertension, and benign prostatic hyperplasia. We all know what erectile dysfunction means, but what is pulmonary arterial hyperplasia and benign prostatic hypertension?

Benign prostatic hyperplasia is the fancier term for an enlarged prostate. This typically causes discomfort as well as either frequent or trouble starting to urinate among other symptoms. Now in terms of pulmonary arterial hypertension, this is the condition that causes an increase in blood pressure within arteries of the lungs. This condition usually causes chest pain, faster than normal heart rate, and a shortness of breath.

Tadalafil works as a treatment for these various types of medical issues because of how it works. It works as an inhibitor of the phosphodiesterase type 5. By inhibiting this specific hormone, it allows the penis to work as it should during arousal. This means that nitric oxide is released in the body allowing the penis to become erect.

So how can a sex enhancement drug effectively aid bodybuilder’s in their endeavors. For starters, many fitness enthusiasts that take anabolic steroids tend to deal with sexual related issues. Meaning that Tadalafil can assist with these types of issues. However, the buck doesn’t stop there. Because it relaxes muscles and allows blood flow to increase users of it typically experience a boost in energy and stamina. By default, this gives you the extra push to pump more iron.

Studies on Tadalafil

Lean Muscle Mass

In this study, men that experience erectile dysfunction as well as diabetes experience a larger waist circumference. The forty three men were on a stable caloric diet.  The goal was to test whether Tadalafil was able to aid in the reduction of waist circumference. Half were assigned to take it and the other half was given a placebo for two months.

In either of the groups, the erectile dysfunction scores improved. In the group given 5mg of Tadalafil daily for that two month span, individuals experienced lean mass development. The reasoning being understood as because of the method in which this compound works, the body created more insulin which aided in the use of consumed sugars being converted into energy instead of fat.3

Muscle Improvements

Several studies exist in today’s resources on therapeutic approaches to Duchenne and Becker Muscle Dystrophy. It has actually become known that by regulating the amount of cGMP in an individual’s body that both dystrophic cardiac and skeletal muscle is improved. How is this done? By the blocking of phosphodiesterase 5.

This is why Tadalafil is considered a contender in aiding this condition. It has the ability to block phosphodiesterase 5 from forming which then decreases the degradation of cGMP. It was found that the compound was able to increase lipid metabolism and increase protein synthesis efficiency among other promising effects.

Effects of Tadalafil

As with many other drugs, there are some mild side effects to be aware of when it comes to Tadalafil. In this case as long as you don’t overdose (meaning you take it more than once a day) the side effects stay in the spectrum of being mild and dissipating with time. Some side effects that you may experience include flushing, headaches or a lightheadedness, and a stuffy nose. Again, these symptoms are normal and usually go away with use. However, if they persist or get worse it is recommended to speak with your doctor.


Several dosing protocols are all over the internet for how to use Tadalafil properly for its medical purposes. But what about those of us looking for the fitness and bodybuilding benefits? Where is that information? So here is what we found.

In many cases, the smallest dose known to have any effects on body composition is 5mg. This was found in the studies mentioned above. The most common dose is 5mg a day if you’re using it for an enlarged prostate, . If using it for erectile dysfunction a 10mg a dose is most common. If you’re someone taking this for a treatment of pulmonary arterial hypertension the recommended dose is 40mg daily or two 20mg tablets. For many reasons, you’ll want to stick within these doses as a method of avoiding overdosing on the compound.

So, what do you say? Are you ready to begin your muscle building journey with the help of Tadalafil? Not sure where you can go to get the best version of this amazing research chemical? We can help with that.

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When going through the many results on Google for where to buy top quality research chemicals. You’ll no doubt come across several manufacturers. But how do you know if you’re getting the best or just getting something else? Truth is you need to trust in your company. That’s why Paradigm Peptides should be on the top of your list. We have all of our products produced and rigorously tested in our labs right here in the good old United States of America. We pride ourselves on getting you the best of the best. Have questions or want to learn more about our products? Check out our blog page or give us a call. We are happy to help you with all your peptide, SARMs, and research chemical needs.

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