Anabolic steroids cause some pretty insane side effects. For those that use them, weighing the pros and cons against one another is a common theme. However, in many cases when taken in access, they cause more harm than good. Sometimes, the side effects are simple enough and sometimes they are more severe. One of the biggest hits to your health and ego is when these substances cause acne to form. Especially when its on your face, chest, and back. This is where the retinoid Isotretinoin comes into play. When you’ve lost all hope and have tried everything from OTC face washes to antibiotics with nothing working, it steps in to save the day.

What are Retinoids?

Retinoids are chemical compounds which are vitamers of vitamin A. This means that it is a compound that exhibits biological effects against a specific vitamin deficiency. In this case, the vitamin is A. In the medical world, these compounds have found a place helping to regulate epithelial cell growth.

When it comes to where retinoids work, the possibilities are endless. They have roles in things life cell proliferation and differentiation, bone tissue growth, vision, and even immune health. However, not all retinoids are the same.

There are three main types. The first generation of retinoids include retinol, tretinoin, isotretinoin, alitretinoin, and retinal. This is the generation that our compound is in. These substances are anti-cancer agents, acne medications, and vitamin A boosters. The second generation of retinoids include etretinate and acitretin. These are both treatments for psoriasis. The third and final generation is the adapalene, bexarotene, and tazarotene. All three of these, as with their first generation, are skin treatments in one form or another.


Isotretinoin which is sold under the brand name Accutane, is a retinoid. Its primary function is to treat severe acne. However, it has also been used in the treatment of various skin cancers and diseases. Once such sickness is known as Harlequin-type ichthyosis. This disorder is when the skin thickens over the entire body at birth resulting in various other difficulties.

Please keep in mind that this product should either be prescribed by a physician or should be taken under the supervision of your physician as it can have some negative side effects.

Studies on Isotretinoin

Nodulocystic Acne

Having any form of acne is uncomfortable let alone nodulocystic acne. This acne affects the face, chest and back. Typically, this type of acne is more common in men and is characterized by multiple inflamed firm lumps known as nodules and cysts. Probably the most unfortunate part involved with this type of acne is the fact that it causes scarring. However, studies have concluded that Isotretinoin can help with this specific type of acne.

In one of these studies, one hundred and fifty patients had this form of acne. It was a double-blind study done in which three different doses were given to the groups involved. Doses of Isotretinoin at 0.1mg/kg, 0.5mg/kg, and 1.0mg/kg were taken daily by the patients to test side effects and the effectiveness of each treatment. Between the three, a high response rate with no major differences between doses. The most pivotal information is that those that received the 0.5mg/kg dose and 1.0mg/kg dose did not need to retreat. However, some of those with the 0.1mg/kg dose did need to retreat after the initial treatments concluded.

Oral Lichen Planus

Oral Lichen Planus is an inflammatory condition that effects the mucous membrane of the inside of your mouth. It results in white patches, red tissue that’s swollen, and open sores. All of which can be very uncomfortable and painful.

However, in a double-blind study, patients with this condition had Isotretinoin gel twice a day as a treatment option. In the treatment ten of the twenty patients applied 0.1% Isotretinoin gel for two months with the others as a placebo group. Those involved in the initial treatments saw a significant improvement in their condition.

Side Effects of Isotretinoin

Several side effects exist and should be monitored while using Isotretinoin. For women, this substance should not be taken if planning to become pregnant or if you are pregnant. This is do to the fact that it can cause multiple issues with the embryo forming. In many instances where a woman becomes pregnant while using this substance, it is a common recommendation to terminate the pregnancy.

In some instances, infections can occur, but this is very rare. Those that take this substance may also experience symptoms such as depression, mood swings, and headaches. Again, these symptoms are also mild in nature and tend to dissipate over time. The most common symptoms involved with taking Isotretinoin relate to the eyes and blood. It can potentially increase the red blood cell sedimentation rate and cause eye irritation or dryness.

If any of the above symptoms persist, speak with your physician.

In many situations, severe acne can be a life altering condition. Not only does it take a toll on you mentally, it affects you physically as well by altering your appearance. No one should have to deal with that and if you’ve tried everything else then maybe it’s time to take further action. Isotretinoin could be exactly what you need to kick your severe acne to the curb and get back to living your best life.

Paradigm Peptides for Severe Acne Relief

When it comes to pharmaceutical grade products, Paradigm Peptides shows up. All of our products undergo testing to ensure the safety of our consumers as well as to make sure that you get the best products. Whether those products be research chemicals like Isotretinoin, or other peptides and SARMs that we carry, you will get the best. Still not sure if it’s the right choice for you. Speak with our customer service about everything from payment options to what peptides, SARMs, or research chemicals could be right for you.

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