Mechano Growth Factor: Bodybuilders Beast It Up | Paradigm Peptides

Are you a beginner in the bodybuilding world or a fitness addict? Or are well-seasoned bodybuilder that has your go tos already mapped out for the coming year? If MGF isn’t part of your regimen, it should be. With the ability to help you with healing and muscle gains, what’s not to like about it.

What is Mechano Growth Factor?

Mechano Growth Factor which also goes by MGF and IGF-1Ec, is a peptide hormone that is produced in muscles in a response to training. The peptide is an isoform of IGF 1. This means that it is comes from the same locus, or location, but are different in their transcription start sites. In most situations, MGF is more abundant in children and adolescence. As we age, we lose our ability to create the peptide on our own. This makes the synthetic version of this peptide the more viable option.

As mentioned above, MGF is typically in the muscle tissue. This also includes skeletal muscle and its main function is to proliferate muscle stem cells. These types of cells are also satellite cells. Because of its mechanisms Mechano Growth Factor can rapidly repair damage done to muscle and promote muscle growth. Within MGF there is a unique E domain in the C terminal. This unique domain distinguishes it from other IGF 1 isoform that exist.

In a newer development, MGF is even a possibility for preventing neuronal attribution and brain dysfunctions. However, these treatments are dose and age dependent. In a study done with Mechano Growth Factor, it showed up within the body after an hour. Not only that, it remained elevated for several weeks after the initial dose.

Studies on Mechano Growth Factor


Neurogenesis is a process where neural stem cells or NCSs produce nervous system cells. In human adults, this occurs in two major areas of the brain, the subventricular and subgranular zones. Age, stress, disease, and exercise of an individual seem to drive this process. Over time, stems cells in these regions of the brain tend to decline. It is important to note that they don’t completely disappear but that they are just less common.

So how does Mechano Growth Factor have anything to do with neurogenesis? As we age and start to lose our ability to create our own NSC. Therefore, by using MGF, can help in maintaining our neural stem cells at what is considered a youthful level.

In an ischemic brain model, MGF showed an ability to have neuroprotective effects. It has even shown potential to be more effective that IGF 1 in this category. In a study completed with aging mice, MGF demonstrated a prevention of neuronal attribution and brain dysfunction.

Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis, or ALS, is a fatal neurodegenerative disorder. motoneuron degeneration typically characterizes it. Also known as destruction of nerve cells. The cells form part of a pathway where impulses pass from the brain or spinal cord to muscles or glands.

There have been several studies conducted to test MGFs ability to aid in neuroprotective effects. MGF has shown to be more effective on neuroprotective effects than IGF 1. Therefore, a study was conducted to see if it is effective in treating ALS. MGF was delivered to the hindlimb muscles of mice that were seventy days old. Through the treatment it was determined that MGF showed significant improvement in hindlimb muscle strength as well as an increase in motor unit and motoneuron survival meaning that more motoneurons survived.

Benefits and Side Effects

Several benefits have been associated with Mechano Growth Factor because of its ability to active muscle stem cells. It then increases the synthesis of proteins that are necessary for tissue growth. MGF can activate the satellite cells which then triggers fusion to muscle fibers and reparation of injury. It is an essential peptide for muscle growth, recovery, and repair.

  • Improve Injury Recovery
  • Increase Muscle Growth
  • Neuroprotective Effects
  • Brain Dysfunction Preventative

Many research trials have been conducted using MGF and found several positives. However, there are a few side effects to keep in mind while taking MGF. For one, a common side effect is hypoglycemia. It is known commonly as low blood sugar. It can be combated by making sure you are keeping an eye on your blood sugar levels. Another common but mild side effect is swelling of extremities. As long as dosing protocol is followed, you limit the possible side effects of MGF.

Dose Protocol 

When it comes to the correct dose for MGF or Mechano Growth Factor, several doses can be consumed per vial. The doses themselves are administered subcutaneously after being reconstituted with a limit of 200mcg per day. The nice thing about this peptide is that you can administer it either after a workout or before bed.

When eating right and working out isn’t enough and an injury occurs, how do you manage? By introducing Mechano Growth Factor into your regimen of supplements for training, of course! This way you can increase your gains and keep your muscles intact.

If you’re just starting out or are a seasoned bodybuilding guru, then MGF peptide is perfect for you. You’ll be able to maintain muscle growth, improve recovery time and keep your brain functioning at optimal levels. Ready to take the next step? Let’s go!

Buying MGF at Paradigm Peptides

Paradigm Peptides has been a leading peptide, SARM, and research chemical manufacturer throughout its existence. Only the best products at the highest quality and purity are manufactured through Paradigm Peptides, meaning that you, the customer, only gets the best. When it comes to MGF it is no different. Each vial has 2mg of this amazing peptide which means you’ll get about 10 days’ worth of peptide per vial. Are you interested in how you can use peptides for therapy? Explore Our Peptide Therapy guide today.

1 thought on “Mechano Growth Factor: Bodybuilders Beast It Up”

Comments are closed.